Journal article

Estimating the impact of test–trace–isolate–quarantine systems on SARS-CoV-2 transmission in Australia

FM Shearer, JM McCaw, GE Ryan, T Hao, NJ Tierney, MJ Lydeamore, L Wu, K Ward, S Ellis, J Wood, J McVernon, N Golding

Epidemics | ELSEVIER | Published : 2024

Abstract

Background: Australian states and territories used test–trace–isolate–quarantine (TTIQ) systems extensively in their response to the COVID-19 pandemic in 2020-2021. We report on an analysis of Australian case data to estimate the impact of test–trace–isolate–quarantine systems on SARS-CoV-2 transmission. Methods: Our analysis uses a novel mathematical modelling framework and detailed surveillance data on COVID-19 cases including dates of infection and dates of isolation. First, we directly translate an empirical distribution of times from infection to isolation into reductions in potential for onward transmission during periods of relatively low caseloads (tens to hundreds of reported cases ..

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Grants

Awarded by Department of Health and Aged Care, Australian Government


Funding Acknowledgements

This work was directly funded by the Australian Government Department of Health and Aged Care. Additional support was provided by the National Health and Medical Research Council of Australia through its Centres of Research Excellence (SPECTRUM, GNT1170960) and Investigator Grant Schemes (JMcV Principal Research Fellowship, GNT1117140; FMS Emerging Leader Fellowship, 2021/GNT2010051) . This research was supported by The University of Melbourne's Research Computing Services and the Petascale Campus Initiative. This work could not have been completed without the support of the public health network in NSW. The Public Health Response Branch, NSW Health including contact tracing staff as well as operational, policy, epidemiology, surveillance, data quality and data acquisition staff contributed to the TTIQ implementation and data provision. In addition, colleagues in the public health units located within the 15 local health districts across the state all contributed to the implementation of the TTIQ strategy.